Exploiting neural plasticity for visual rehabilitation 

Brief perturbations to sensory experience have the capacity to drive lifelong changes in the nervous system. We are interested in understanding the consequences of such sensory perturbations on neural activity, and how to recapitulate this activity to drive long-lasting therapeutic plasticity. In this talk, I present examples of how we have tackled these goals in animal models of amblyopia, a widespread form of human visual impairment. I first discuss the plasticity that underlies amblyopia, and critical periods for both the development of disability and response to treatment. Next, I will present work we have done to identify and validate plasticity-based interventions for treating amblyopia in mice and cats. I then present ongoing work on our efforts to understand how activity and plasticity in the early visual pathway contribute to visual recovery. I conclude with a broad outlook on the synergy between high-tech neuroprosthetics and low-cost simple therapeutics to advance both basic and translational research.

Ming-fai Fong, PhD 

Assistant Professor Coulter Department of Biomedical Engineering Georgia Institute of Technology and Emory University

Faculty Host: Alecia K. Gross, PhD, FARVO

On-site attendance may account for one Alabama CE credit for ODs.

Please RSVP to Nakia Lee by March 7th.