CCVC Seminar Series Spring 2024 - Daniel Tyrrell, PhD 

Topic: Exploring CD8+ T cells in atherosclerosis and brain aging 

Learning objectives: 

1. CD8+ T cell subsets and phenotype are significantly altered by aging in mice and humans. 
2. Age-related changes in CD8+ T cell subsets promote atherosclerosis in mice.
3. A population of Granzyme-K expressing T cells accumulates in aging and has a pro-inflammatory phenotype